分析结果显示，心力衰竭前期的受试者中，与不饮酒相比，中度饮酒和大量饮酒组的心脏健康恶化风险增加4.5倍，更有可能进展为有症状的心力衰竭。“我们的研究表明，欧洲人每周饮酒超过 70 克与心力衰竭前期的恶化或进展为症状性心力衰竭有关。研究人员强调。“这一结果意味着，我们发现的安全量只有爱尔兰建议的每周酒精摄入量的一半不到。”
 Alcohol may be more risky to the heart than previously thought。 Retrieved May 31， 2022 from https：//www.eurekalert.org/news-releases/953314
 Bethany Wong （2022） Moderate alcohol consumption is associated with progression of left ventricular dysfunction in a European stage B heart failure population。
Although restrictions on alcohol consumption vary around the world, below the so-called "recommended" or "safe" levels in some areas, alcohol consumption can still be found to be closely related to the development of heart failure.
The researchers focused on a species called "Alcoholic cardiomyopathy”的心力衰竭.这种疾病的罪魁祸首就是酒精，由于酒精以及酒精在人体内的代谢产物——乙醛对心肌有直接毒害，日结月累，心肌会变得像被牵扯过度的橡皮筋，弹性变差，无法有效地泵送血液.
Alcoholic cardiomyopathy is usually thought to be the result of long-term heavy drinking.. The so-called "large amount", in Ireland, for example, is defined as more than 110 grams of pure alcohol per week for women and 170 grams for men. But in this study, researchers at St. Vincent University Hospital in Dublin, Ireland, foundActuallyIt is still dangerous to drink below this amount..
The researchers analyzed more than 700 subjects who were at high risk of heart failure (such as high blood pressure, diabetes, obesity, etc.) or in the early stages of heart failure (with these risk factors and heart abnormalities, but had not yet developed symptoms). Their heart function was measured by echocardiography and followed up for an average of 5.4 years to investigate the relationship between heart health and alcohol intake.
According toWeekly pure alcohol intakeThe researchers divided the subjects into four groups:
Drink a small amount of alcohol (less than 70 grams, equivalent to up to a bottle of 750 ml 12.5% wine, or three and a half cans of 4.5% beer with 500 ml each)
Moderate alcohol consumption (70g ~ 140g, equivalent to up to two bottles of 12.5% wine, or seven cans of 4.5% beer)
Drink heavily (more than 140 grams, equivalent to more than two bottles of 12.5% wine or more than seven cans of 4.5% beer).
The analysis results show thatAmong subjects in the early stages of heart failure, moderate and heavy drinking groups had a 4.5-fold increased risk of deteriorating heart health compared with non-drinking groups, and were more likely to progress to symptomatic heart failure.. "our research shows that Europeans drinking more than 70 grams a week is associated with the deterioration or progression of symptomatic heart failure in the early stages of heart failure. The researchers stressed. "this result means thatThe safe amount we found was less than half of Ireland's recommended weekly alcohol intake."
Among high-risk subjects, moderate or heavy drinking was not associated with progression to pre-heart failure or symptomatic heart failure. In additionThe results of the study did not find that a small amount of alcohol consumption had any protective effect..
It is worth mentioning that the study focused on heavy drinkers in Europe, while some evidence from Asian populations suggests that lower alcohol intake may cause myocardial damage in Asians than in Europeans. Due to genetic differences, many Asians are unable to metabolize alcohol smoothly, causing more damage to alcohol and its metabolites in the body. in other words, Asians are less resistant to alcohol.
Maybe some people drink to be happy, but all kinds of research evidence tells us that alcohol can cause real "sadness".. "this study adds a lot of evidence that drinking should be treated more cautiously," said study author Dr. Bethany Wong. "in order to minimize the risk of heart damage caused by alcoholDon't start drinking if you can't drink. Drinkers had better limit their weekly consumption to less than one bottle of wine or three and a half cans of beer..
 Alcohol may be more risky to the heart than previously thought . Retrieved May 31, 2022 from https://www.eurekalert.org/news-releases/953314
Bethany Wong (2022) Moderate alcohol consumption is associated with progression of left ventricular dysfunction in an European stage B heart failure population.
This article is from the Wechat team of Yao Ming Kant content.